Repositioning Natural Products in Drug Discovery
نویسندگان
چکیده
منابع مشابه
Natural products in drug discovery.
Natural products have been the single most productive source of leads for the development of drugs. Over a 100 new products are in clinical development, particularly as anti-cancer agents and anti-infectives. Application of molecular biological techniques is increasing the availability of novel compounds that can be conveniently produced in bacteria or yeasts, and combinatorial chemistry approa...
متن کاملNatural products and drug discovery
The medicinal use of natural products—compounds that are derived from natural sources such as plants, animals or micro-organisms—precedes recorded human history probably by thousands of years. Palaeoanthropological studies at the cave site of Shanidar, located in the Zagros Mountains of Kurdistan in Iraq, have suggested that more than 60,000 years ago, Neanderthals might have been aware of the ...
متن کاملMarine natural products in drug discovery
Marine organisms comprise approximately a half of the total biodiversity, thus offering a vast source to discover useful therapeutics. In recent years, a significant number of novel metabolites with potent pharmacological properties have been discovered from the marine organisms. Although, there are only few marine derived products currently in the market, several marine natural products are no...
متن کاملDrug Discovery, CAM and Natural Products
This editorial is related to two papers in volume 1 issue 2 of eCAM and to others concerned with molecules derived from terrestrial and marine species (1–15). These papers focus on natural products, especially those derived from the sea. Therefore, it is appropriate to apply the contributions of these papers, since they can offer a different perspective. It is, indeed, a matter of great coincid...
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ژورنال
عنوان ژورنال: Molecules
سال: 2020
ISSN: 1420-3049
DOI: 10.3390/molecules25051154